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. 2024 Jul 1;15:1418309. doi: 10.3389/fimmu.2024.1418309

Figure 2.

Figure 2

Forest plot of the Mendelian randomization analyses for the associations between circulating cytokine levels and the risk of neuromyelitis optica spectrum disorder. Forest plot of the MR results for the relationships between circulating cytokines and the risk of AQP4-ab-positive NMOSD (A) and AQP4-ab-negative NMOSD (B). No., number; OR, odds ratio; CI, confidence interval; IL-1α, interleukin-1α; IL-2, interleukin-2; IL-2Rβ, interleukin-2 receptor β; IL-4, interleukin-4; IL-6, interleukin-6; IL-7, interleukin-7; IL-8. interleukin-8; IL-10, interleukin-10; IL-10Rα, interleukin-10 receptor α; IL-10Rβ, interleukin-10 receptor β; IL-12β, interleukin-12β; IL-13, interleukin-13; IL-17A, interleukin-17A; IL-18, interleukin-18; IL-20, interleukin-20; IL-24, interleukin-24; IL-33, interleukin-33; IFN-γ, interferon-gamma; TGF-β, transforming growth factor β; CCL4, C-C motif chemokine 4; CCL19, C-C motif chemokine 19; CCL20, C-C motif chemokine 20; CCL23, C-C motif chemokine 23; CCL25, C-C motif chemokine 25; CCL28, C-C motif chemokine 28; CXCL1, C-X-C motif chemokine 1; CXCL5, C-X-C motif chemokine 5; CXCL6, C-X-C motif chemokine 6; CXCL9, C-X-C motif chemokine 9; CXCL10, C-X-C motif chemokine 10; CXCL11, C-X-C motif chemokine 11; SNPs, single nucleotide polymorphisms.