Table 1.
Demographic and clinical parameters of T1D and HC cohort.
| HC (n = 37) |
T1D | ||||
|---|---|---|---|---|---|
| In total (n = 242) |
T1D-group-A (n = 50#) |
T1D-group-B (n = 191#) |
p-values (group-A vs -B) | ||
| Age (years) | 53 ± 10 | 52 ± 16 | 54 ± 16 | 52 ± 16 | 0.55 |
| Male sex (%) | 50% | 54% | 66% | 51% | 0.07 |
| BMI (Kg/m2) | 24.4 ± 3.6 | 25.9 ± 4.3 * (5 missing values) |
26.4 ± 4.3* (2 missing values) |
25.7 ± 4.4* (3 missing values) |
0.29 |
| Disease duration (years) | — | 29 ± 16* (2 missing values) |
28 ± 16 | 29 ± 15* (2 missing values) |
0.77 |
| Onset-age of T1D(years) | — | 23 ± 14* (2 missing values) |
25 ± 16 | 23 ± 13* (2 missing values) |
0.63 |
| Onset-age <= 7years | — | 10%* (2 missing values) |
12% | 10%* (2 missing values) |
0.61 |
| Insulin usage (unit/kg) | — | 0.66 ± 0.45* (7 missing values) |
0.70 ± 0.48* (2 missing values) |
0.65 ± 0.43* (5 missing values) |
0.59 |
| HbA1c level (mmol/mol) | — | 64 ± 15* (1 missing value) |
63 ± 13 | 64 ± 15* (1 missing value) |
0.91 |
| hsCRP (µg/ml) | — | 1.8 ± 2.5 | 2.2 ± 3.6 | 1.7 ± 2.1 | 0.38 |
| Macrovascular compl. | — |
17%* (2 missing values) |
35% |
14% * (2 missing values) |
0.02 |
| Coronary arterial disease | — | 10%* (2 missing values) |
16% | 8%* (2 missing values) |
0.12 |
| Peripheral arterial disease | — | 7%* (2 missing values) |
10% | 6%* (2 missing values) |
0.39 |
| Stroke | — | 6%* (2 missing values) |
12% | 4%* (2 missing values) |
0.06 |
| Microvascular compl. | — |
73%* (20 missing values) |
78%*
(5 missing values) |
72%*
(15 missing values) |
0.45 |
| Nephropathy | — | 18%* (4 missing values) |
24% | 17%* (4 missing values) |
0.29 |
| Neuropathy | — | 47%* (5 missing values) |
52% | 47%* (5 missing values) |
0.54 |
| Retinopathy | — | 64%* (28 missing values) |
65%* (7 missing values) |
64%* (21 missing values) |
0.95 |
1. Demographic characteristics were shown as mean ± S.D.
2. Patients with macro-/micro-vascular complications were defined as ‘yes’’ when at least one of the three-listed complications present.
3. #One T1D patient was classified neither to T1D-group-A nor T1D-group-B. Thus, it is skipped during the detailed comparison between patient subgroups.
4. *Missing values exist for the corresponding variables.
5. BMI, body mass index; hsCRP, high-sensitivity C-reactive protein; compl., complications.