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. 2024 Jul 1;14:1386909. doi: 10.3389/fonc.2024.1386909

Table 2.

Analysis of factors associated with intracranial progression free survival following diagnosis of brain metastases.

IC-PFS UVA MVA
Median(m) P value P value HR 95%CI for HR
Lower Upper
Age <40yrs 11.0
>40yrs 14.1 0.493 0.507 0.89 0.123 2.084
ER Positive 17.1
Negative 12.0 0.448 0.833 2.559 0.39 2.13
PR Positive 17.1
negative 13.6 0.389 0.084 2.656 0.169 1.118
Ki-67 ≥50% 7.0
<50% 17.1 0.065 0.012 2.989 0.116 0.761
Her2 targeted therapy Yes 20
No 14 0.037 0.046 3.998 1.028 15.324
ECOG score 0-1 20
2-4 13.6 0.97 0.204 1.617 0.292 1.3
Tumor burden Low 20
High 9.0 0.003 0.025 4.991 1.129 6.411

Tumor burden means the intracranial tumor.