Table 4.
Mendelian randomization estimates of the causal relationships between serum uric acid levels and cancer risk using MR-Egger and Weighted median method.
| Population | nsnp | Colorectal cancer | Colon cancer | Rectal cancer | |||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||
| MR-Egger | |||||||
| Overall | 26 | 1.0046 (0.9851, 1.0245) | 0.652 | 1.0046 (0.9851, 1.0246) | 0.652 | 0.9959 (0.9896, 1.0022) | 0.216 |
| Male | 26 | 0.9994 (0.9963, 1.0025) | 0.721 | 1.0038 (0.9874, 1.0205) | 0.657 | 0.9965 (0.9915, 1.0015) | 0.181 |
| Female | 26 | 0.9997 (0.9976, 1.0018) | 0.773 | 1.0047 (0.9824, 1.0274) | 0.687 | 0.9972 (0.9903, 1.0041) | 0.433 |
| Weighted median | |||||||
| Overall | 26 | 1.0022 (0.9979, 1.0065) | 0.316 | 1.0022 (0.9979, 1.0065) | 0.316 | 0.9992 (0.9973, 1.0010) | 0.357 |
| Male | 26 | 0.9990 (0.9967, 1.0014) | 0.433 | 1.0020 (0.9982, 1.0057) | 0.301 | 0.9993 (0.9977, 1.0008) | 0.340 |
| Female | 26 | 0.9937 (0.9977, 1.0011) | 0.467 | 1.0023 (0.9976, 1.0070) | 0.339 | 0.9992 (0.9974, 1.0012) | 0.402 |
OR, odds ratio; CI, confidence interval.