Table.

Clinical details of patients with primary HIV infection

	Case 1	Case 2	Case 3
Clinical features:
At presentation	Fever, headaches, confusion, rash (limbs), nausea	Flu-like illness, headache, sore throat	Flu-like illness, sore throat, nausea, diarrhoea
Subsequent	Obtunded, grand mal seizures	Headaches, meningism, maculopapular rash, nausea, lymphadenopathy, oral ulcers	Headache, meningism, generalised rash, lymphadenopathy
Time delay for diagnosis of infection*	3 days	8 days	9 days
Neurological diagnosis	Meningoencephalitis	Meningitis	Meningitis

Patients had primary HIV infection with presence of anti-HIV immunoglobulin M antibodies (n=1) or evolving HIV specific antibody profile (n=2). All described febrile illness preceding onset of headaches. Three had had a rash (two had received antibiotics) and two had had upper respiratory tract symptoms. 

^*Calculated from day of initial presentation to day that first positive HIV test result was confirmed.