TABLE 3.

The binding energy values of core compounds of epimedium and core targets.

Target	Compounds	Binding affinity/(kcal/mol)
AKT1 (4GV1)	Baohuoside I	−4.61
	Icariin	−4.63
	Hyperoside	−5.29
	Epimedin B	−2.68
JUN (2P33)	Baohuoside I	−3.17
	Icariin	−1.79
	Hyperoside	−2.02
	Epimedin B	−1.45
IL6 (5SFK)	Baohuoside I	−3.40
	Icariin	−1.22
	Hyperoside	−1.84
	Epimedin B	−1.82
SRC (3SOS)	Baohuoside I	−4.12
	Icariin	−2.51
	Hyperoside	−2.78
	Epimedin B	−2.62
EGFR (3IKA)	Baohuoside I	−5.13
	Icariin	−2.84
	Hyperoside	−3.91
	Epimedin B	−1.25
BCL2 (6U64)	Baohuoside I	−3.34
	Icariin	−2.54
	Hyperoside	−2.18
	Epimedin B	−1.05