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LILRB3’s predicted interaction domains with HLA molecules. Based on sequence alignment, several interaction sites with class I HLA are found on LILRB3 proteins. Domains 1 and 2 are predicted to mainly link the β2-microglobulin HLA class I invariant chain, whereas domains 3 and 4 are predicted to link several polymorphic HLA class I α-chains. Created with ggalluvial R package and BioRender.com.
