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Immunologic synapse hypothesis between the donor’s renal cell and the recipient’s monocytic cell. ANGPTL, Angiopoietin-Like; APOE, Apolipoprotein-E; PI3K, Phosphoinositide 3 Kinase; DSA, Donor Specific Antibody; HLA, Human Leukocyte Antigen; ITAM, Immunoregulatory Tyrosin-based Activator Motifs; ITIM, Immunoregulatory Tyrosin-based Inhibitory Motifs; LILR, Leukocyte Immunoglobulin Like Receptor. Created with BioRender.com.
