TABLE 1.
Virus strain or mutant | Species and/or cell type | In vitro transformation experiments (no. positive/total)a | Pathogenesis (survival time in days)b |
---|---|---|---|
C488 | Human CBL | 8/13 | NA |
C. jacchus PBMC | 9/9 | ND | |
S. oedipus PBMC | 10/10 | 15 | |
C488ΔFLIP | Human CBL | 7/13 | NA |
C. jacchus PBMC | 9/9 | ND | |
S. oedipus PBMC | 10/10 | 14, 15 |
Performed with human CBL (13 donors) and PBMC from C. jacchus (5 donors) and S. oedipus (10 donors). Parallel cultures of cells were infected with herpesvirus saimiri C488 or C488ΔFLIP.
NA, not applicable; ND, not done.