TABLE 1.
Characteristics of study participants at the last visit prior to death (n = 596).
| Characteristics | Mean (SD) or n (%) |
|---|---|
| Age at death baseline, years, mean (SD) | 89.6 (6.4) |
| Women, n (%) | 410 (69) |
| Education, years, mean (SD) | 15.4 (3.4) |
| White non‐Hispanic, n (%) | 576 (97) |
| Mini‐Mental State Examination score, mean (SD) | 22.4 (8.3) |
| Global cognition | −0.79 (1.07) |
| Alzheimer's dementia, n (%) | 200 (34) |
| Post mortem pathological assessment | |
| Pathological diagnosis of AD, n (%) | 371 (62) |
| Immunohistochemical assessments | |
| Square root of Aβ load, mean (SD) | 1.6 (0.78) |
| Square root of tau tangle density, mean (SD) | 1.44 (1.11) |
| TDP‐43 | 174 (29) |
| Hippocampal sclerosis | 47 (8) |
| Lewy bodies | 149 (25) |
| Macroinfarcts | 193 (32) |
| Microinfarcts | 164 (28) |
| Moderate to severe atherosclerosis | 189 (32) |
| Moderate to severe arteriolosclerosis | 191 (32) |
| Moderate to severe cerebral amyloid angiopathy | 180 (30) |