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. 2024 Jun 12;20(7):4411–4422. doi: 10.1002/alz.13823

TABLE 1.

List of 87 unique genes

No. Protein name Gene name
1 p‐gp/ABCB1 ABCB1
2 pAkt(Ser473), Akt (panel) AKT1
3 Aβ40, Aβ42, sAPPa, sAPPb APP
4 BACE‐1 BACE1
5 pBADSer136 BAD
6 Butyrylcholinesterase BCHE
7 BDNF BDNF
8 C1 complement complex – C1q C1QA
9 Complement C3b, Complement C3d C3
10 Complement fragment C4b C4B
11 Terminal complement complex C5b‐C9 C5
12 CD46 CD46
13 DAF (CD55) CD55
14 CD59 CD59
15 CD63 CD63
16 CD81 CD81
17 CD9 CD9
18 Complement B, Complement factor B–Bb, Factor B CFB
19 Complement factor D CFD
20 Factor I CFI
21 Clusterin CLU
22 CR1 CR1
23 CRP CRP
24 Cystatin C CST3
25 Cathepsin D CTSD
26 NS‐enolase ENO2
27 FGF‐13 FGF13
28 FGF‐2 FGF2
29 GAP43 GAP43
30 GDNF GDNF
31 GFAP GFAP
32 GluSyn GLUL
33 AMPA4 GRIA4
34 PGRN GRN
35 pGSK‐3B(Ser9), GSK‐3β GSK3B
36 Gelsolin GSN
37 HGF HGF
38 HSF1 HSF1
39 HSP70 HSPA1A
40 ICAM1 ICAM1
41 IGF‐1 IGF1
42 p‐IGF‐1R IGF1R
43 IL‐1β IL1B
44 IL‐6 IL6
45 pIR INSR
46

P‐serine 312‐IRS‐1, p‐panTyr‐IRS‐1, Total IRS‐1,

p‐panTyr‐IRS‐1, Ser616‐IRS‐1, pIRS1(Ser636)

IRS1
47 L1CAM L1CAM
48 LAMP‐1 LAMP1
49 LRP6 LRP6
50 Erk1/2 MAPK1
51 P38 MAPK MAPK11
52 JNK MAPK8
53

PTau‐T181, PTau‐S202, PTau‐S231, PTau‐S396,

PTau‐T205, T‐tau, Tau N‐123, Full length tau

MAPT
54 MBL MBL2
55 MMP‐9 MMP9
56 MOG MOG
57 mTOR, pmTORSer2448 MTOR
58 NCAM‐1 NCAM1
59 NFL NEFL
60 NLGN1 NLGN1
61 NPTX2 NPTX2
62 Neurogranin NRGN
63 NRXN2alfa NRXN2
64 OMG OMG
65 Alix PDCD6IP
66 G‐secretase PSENEN
67 pPTEN(Ser380) PTEN
68 REST REST
69 p70S6K(T389), pS6Ser235/Ser236 RPS6KB1
70 Syntenin‐1 SDCBP
71 GLAST SLC1A3
72 Glut‐1 SLC2A1
73 LAT‐1 SLC7A5
74 SNAP‐25 SNAP25
75 Alpha‐synuclein SNCA
76 Syntaxin 1 STX1A
77 Synapsin 1 SYN1
78 Synaptopodin SYNPO
79 Synaptophysin SYP
80 Synaptotagmin‐1 SYT1
81 Synaptotagmin‐2 SYT2
82 TDP‐43 TARDBP
83 TNF‐α TNF
84 TSG101 TSG101
85 Ubiquitin UBB
86 UCH‐L1 UCHL1
87 VAMP‐2 VAMP2