Table 7.
Logistic regression with converters (1) and non-converters (0) as the dependent variable involving 120 patients with complete data including APOE ɛ4-carrier status.
| Unadjusted model | Adjusted model 1 | Adjusted model 2 | ||||
|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | OR (95%CI) | p | |
| Age | 1.08 (1.03–1.12) | 0.001 | 1.06 (0.99–1.13) | 0.125 | 1.05 (0.98–1.13) | 0.162 |
| Sex | 0.72 (0.31–1.64) | 0.431 | 0.68 (0.27–1.74) | 0.421 | 0.66 (0.26–1.71) | 0.394 |
| Education | 0.93 (0.83–1.06) | 0.276 | ||||
| Whole brain volume | 0.88 (0.79–0.99) | 0.026 | 0.93 (0.79–1.08) | 0.336 | 0.93 (0.79–1.09) | 0.349 |
| Follow-up time | 1.03 (1.00–1.05) | 0.029 | 1.03 (1.00–1.06) | 0.033 | 1.04 (1.01–1.07) | 0.019 |
| MRI NQ before 2015 | 1.12 (0.49–2.57) | 0.788 | ||||
| MMSE-NR score | 0.86 (0.73–1.02) | 0.091 | 0.87 (0.72–1.05) | 0.149 | ||
| APOE ε4-carrier | 2.64 (1.12–6.19) | 0.026 | 1.48 (0.57–3.85) | 0.423 | 1.36 (0.51–3.61) | 0.538 |
| R 2 | 0.21 | 0.23 | ||||
Whole brain volume as the independent variable.
Values in bold are significant, OR: odds ratio; CI: confidence interval; R2: explained variance; NQ: NeuroQuant®; MMSE-NR: Mini-Mental State Examination-Norwegian revision.