Table 8.
Linear regression analysis of annual change in CDR-SB scores involving 100 patients with complete data, including APOE ɛ4-carrier status.
| Unadjusted model | Adjusted Model 1 | Adjusted model 2 | ||||
|---|---|---|---|---|---|---|
| β (SE) | p | β (SE) | p | β (SE) | p | |
| Age | 0.33 (0.001) | 0.004 | 0.15 (0.001) | 0.148 | 0.16 (0.001) | 0.119 |
| Sex | −0.42 (0.013) | 0.677 | −0.11 (0.011) | 0.235 | −0.08 (0.011) | 0.328 |
| Education | −0.16 (0.002) | 0.119 | −0.76 (0.002) | 0.408 | ||
| Hippocampus percentile | −0.45 (<0.001) | <0.001 | −0.38 (<0.001) | <0.001 | −0.33 (0.000) | 0.003 |
| MMSE-NR score | −0.25 (0.003) | 0.011 | −0.17 (0.003) | 0.084 | ||
| Follow-up time | 0.26 (0.000) | 0.011 | 0.22 (<0.001) | 0.017 | 0.26 (0.00) | 0.007 |
| MRI NQ before 2015 | 0.12 (0.013) | 0.236 | ||||
| NQ version 1or 2 | 0.00 (0.032) | 0.989 | ||||
| MMSE-NR score | −0.25 (0.003) | 0.011 | −0.17 (0.003) | 0.084 | ||
| APOE ε4-carrier | 0.18 (0.012) | 0.078 | 0.03 (0.012) | 0.795 | −0.01 (0.012) | 0.888 |
| R 2 | 0.29 | 0.32 | ||||
Hippocampus percentile as the independent variable.
Values in bold are significant. β: coefficient; SE: standard error; R2: explained variance; NQ: NeuroQuant®; MMSE-NR: Mini-Mental State Examination-Norwegian revision.