Table 3.

Association between baseline GSLTPAQ scores and changes in QoL metrics as measured by FACIT Fatigue or Dyspnea over time^*

		Change in QoL measure in breast cancer, according to physical activity (n = 80)		Change in QoL measure in lung cancer and lymphoma, according to physical activity (n = 50)
Baseline physical activity measure	QoL measure	β-coefficient (95% CI)†	P value	β-coefficient (95% CI)†	P value
Baseline overall GSLTPAQ score
	FACIT Fatigue score	0.5 (0–1.0)	.070	0.6 (−0.4 to 1.5)	.229
	FACIT Dyspnea score	−0.3 (−0.7 to 0)	.065	−0.1 (−0.6 to 0.4)	.706
Baseline GSLTPAQ MVPA score
	FACIT Fatigue score	0.5 (0–1.0)	.060	0.3 (−0.6 to 1.2)	.498
	FACIT Dyspnea score	−0.2 (−0.5 to 0.0)	.087	−0.1 (−0.6 to 0.4)	.683

Abbreviations: CI = confidence interval; FACIT = Functional Assessment of Chronic Illness Therapy; GSLTPAQ = Godin—Shephard Leisure-Time Physical Activity Questionnaire; MVPA = moderate-to-vigorous physical activity; QoL = quality of life.

^*Generalized estimating equation linear regression modeled the association between the change in each QoL measure from baseline and baseline physical activity scores. Models were adjusted for age, sex (for lung cancer and lymphoma only), mean heart dose, radiation therapy duration, chemotherapy exposure (none or preceding/concurrent), time point of assessment, and baseline FACIT score. Note that higher overall GSLTPAQ and GSLTPAQ MVPA scores indicate greater physical activity, higher FACIT fatigue scores indicate less fatigue, and higher FACIT dyspnea scores indicate worse dyspnea.

^†β-coefficients represent the difference in the change from baseline at each post—radiation therapy time point for a given QoL outcome measure for each 10-point increase in overall GSLTPAQ or GSLTPAQ MVPA score at baseline.