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. Author manuscript; available in PMC: 2024 Jul 15.
Published in final edited form as: Endocr Relat Cancer. 2023 Nov 22;31(1):e230196. doi: 10.1530/ERC-23-0196

Figure 1. CTLA4 is expressed by hormone-secreting cells of the normal human anterior pituitary gland.

Figure 1.

Quantification of CTLA4 mRNA expression by RNAscope in 50 normal pituitary specimens by H-score (A) and percentage of positive cells (B). Representative RNAscope staining for CTLA4 in a low expressing (C) and high expressing (D) pituitary gland. The red arrow in D indicates a cluster of CTLA4 mRNA transcripts. Each red dot represents one CTLA4 mRNA copy. Immunohistochemical staining of two normal pituitary glands for CTLA4 shows focal expression with differences in staining intensity (E and F) and involved areas (E and F, inset).