Table 2.
Brain hemorrhages by treatment group
| All (n = 470) | Epo (n = 240) | Placebo (n = 230) | Group comparison (95% CI) | |
|---|---|---|---|---|
| Intraparenchymal | 1.30 (0.77, 2.19)* | |||
| None | 404 (86) | 203 (85) | 201 (87) | |
| Trace | 41 (9) | 20 (8) | 21 (9) | |
| Mild/mod | 18 (4) | 12 (5) | 6 (3) | |
| Severe | 7 (1) | 5 (2) | 2 (1) | |
| Intraventricular | 1.54 (0.98, 2.44)* | |||
| None | 376 (80) | 184 (77) | 192 (83) | |
| Trace | 70 (15) | 41 (17) | 29 (13) | |
| Mild/mod | 13 (3) | 7 (3) | 6 (3) | |
| Severe | 11 (2) | 8 (3) | 3 (1) | |
| Subdural | 1.09 (0.75, 1.59)* | |||
| None | 318 (68) | 162 (68) | 156 (68) | |
| Trace | 89 (19) | 40 (17) | 49 (21) | |
| Mild/mod | 55 (12) | 32 (13) | 23 (10) | |
| Severe with mass effect | 8 (2) | 6 (3) | 2 (1) | |
| Subarachnoid | 0.85 (0.34, 2.13)* | |||
| None | 451 (96) | 231 (96) | 220 (96) | |
| Questionable/trace | 12 (3) | 6 (3) | 6 (3) | |
| Focal | 7 (1) | 3 (1) | 4 (2) | |
| Diffuse | 0 (0) | 0 (0) | 0 (0) |
*Odds ratio and 95% CI estimated with proportional odds regression model, adjusted for HIE severity and site.