Table 1.
Subject characteristics by genotype at rs10830963
| Genotype at rs10830963 | CC | CG/GG | P-value |
|---|---|---|---|
| n | 148 | 146 | |
| Age (years) | 57 ± 1 | 56 ± 1 | 0.58 |
| M/F | 67/81 | 60/86 | |
| Weight (kg) | 80 ± 1 | 79 ± 1 | 0.61 |
| BMI (kg/M2) | 27.5 ± 0.4 | 27.4 ± 0.4 | 0.86 |
| LBM (kg) | 46 ± 1 | 45 ± 1 | 0.31 |
| Fasting glucose (mmol/L) | 5.52 ± 0.05 | 5.57 ± 0.04 | 0.46 |
| Peak glucose (mmol/L) | 10.5 ± 0.1 | 11.0 ± 0.1 | 0.02 |
| 120-minute glucose (mmol/L) | 8.3 ± 0.2 | 8.5 ± 0.2 | 0.51 |
| Fasting insulin (pmol/L) | 37 ± 2 | 35 ± 2 | 0.46 |
| Peak insulin (pmol/L) | 455 ± 28 | 437 ± 23 | 0.63 |
| Fasting glucagon (ng/L) | 76 ± 2 | 82 ± 2 | 0.02 |
| Nadir glucagon (ng/L) | 54 ± 1 | 58 ± 1 | 0.04 |
Abbreviations: BMI, body mass index; LBM, lean body mass.