Table 1.

Patients and subgroup characteristics

	Males	Mean age (years)	Females	Mean age (years)
Overall
ISS < 16	216	42.8 ± 18.2	89	42.1 ± 21.1
ISS ≥ 16	93	50.3 ± 19.1	38	53.6 ± 25.4
Overall	309	45.0 ± 18.8	127	45.5 ± 22.9
Control group
ISS < 16	59	42.7 ± 18.2	20	38.1 ± 20.4
ISS ≥ 16	45	43.8 ± 16.9	17	46.1 ± 24.3
Overall	104	43.1 ± 17.6	37	41.7 ± 22.3
Interim group
ISS < 16	29	42.3 ± 18.3	19	44.8 ± 15.5
ISS ≥ 16	6	57.0 ± 15.3	2	40.5 ± 46.0
Overall	35	44.8 ± 18.5	21	44.4 ± 18.0
Transition group
ISS < 16	43	42.2 ± 19.0	12	50.8 ± 22.1
ISS ≥ 16	16	51.4 ± 19.6	6	59.3 ± 20.5
Overall	59	45.5 ± 19.3	18	53.7 ± 21.4
Routine use group
ISS < 16	85	42.8 ± 18.1	38	40.1 ± 23.2
ISS ≥ 16	26	59.4 ± 19.5	13	62.7 ± 25.1
Overall	111	46.7 ± 19.7	51	45.8 ± 25.4