Table 3.

Diagnostic accuracy of BCAAs for ASD

	Total BCAAs (μmol/L)	Val (μmol/L)	Leu (μmol/L)	Model
Cut-off value	283.26	153.58	138.17	-
AUC (95% CI)	0.734 (0.651–0.817)	0.686 (0.599–0.773)	0.753 (0.673–0.834)	0.756 (0.676–0.835)
Sensitivity (%)	88.24	80.0	85.88	78.82
Specificity (%)	52.94	54.41	58.82	66.18
PPV (%)	70.09	68.69	72.28	74.44
NPV (%)	78.26	68.52	76.92	71.43
P-value	< 0.001	< 0.001	< 0.001	0.001

BCAAs branched-chain amino acids, AUC area under the curve, CI confidence interval, NPV negative predictive value, PPV positive predictive value, Val valine, Leu leucine/isoleucine. Model, the combined nomogram model of BCAAs