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. 2024 May 23;416(18):4015–4028. doi: 10.1007/s00216-024-05339-0

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© The Author(s) 2024

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Fig. 2 — Effect of the DESI heated transfer line (HTL) temperature at 150 °C and 450 °C on different molecular classes of kidney tissue. Differences in a the negative ionization mode mass spectra of a kidney tissue analyzed with HTL at 150 °C (black) and 450 °C (blue); and b mass spectrum of m/z 124.0074 (taurine) showing higher intensity with HTL at 450 °C (n = 3). c DESI ion images showing increased sensitivity for m/z 734.5048, m/z 734.5137, and m/z 778.5298 with the HTL at 450 °C in comparison to 150 °C