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Titration of HIV-1 inhibition by Met-SDF-1β versus wild-type SDF-1β. Primary CD4+ cells were pretreated for 2 h with the indicated concentrations of each form of SDF-1β, infected with HIV-1 IIIB, and cultured with the indicated concentration of chemokine as for Fig. 1. HIV-1 p24 antigen concentrations were done at 3-day intervals; values for day 6 are shown.
