Table 4.
Changes in the obesity indices and metabolic control parameters.
| Time | Estimated mean levels (95%CI) | Estimated mean difference from T0 and 95% CI | p-value* | |
|---|---|---|---|---|
| BMI (Kg/m2) | T0 | 34.65 (33.26;36.05) | ||
| T6 | 31.47 (28.83;34.11) | -3.18 (-5.54;-0.83) | 0.009 | |
| T12 | 32.91 (31.32;34.5) | -1.74 (-2.72;-0.77) | 0.0006 | |
| Waist circumference (cm) | T0 | 115.6 (112.51;118.68) | ||
| T6 | 112.98 (109.73;116.23) | -2.62 (-4.29;-0.95) | 0.002 | |
| T12 | 113.22 (109.65;116.78) | -2.38 (-4.82;0.07) | 0.06 | |
| HbA1c (%) | T0 | 7.71 (7.46;7.97) | ||
| T6 | 6.62 (6.37;6.87) | -1.10 (-1.43;-0.76) | <0.0001 | |
| T12 | 6.64 (6.37;6.9) | -1.07 (-1.39;-0.76) | <0.0001 | |
| FBG (mg/dl) | T0 | 150.75 (142.28;159.22) | ||
| T6 | 117.51 (111.86;123.16) | -33.24 (-41.87;-24.61) | <0.0001 | |
| T12 | 126.08 (113.66;138.51) | -24.67 (-37.29;-12.04) | 0.0002 | |
| SBP (mmHg) | T0 | 136.25 (131.55;140.95) | ||
| T6 | 133.7 (127.4;140) | -2.55 (-9.54;4.45) | 0.47 | |
| T12 | 126.99 (120.72;133.26) | -9.26 (-17.11;-1.4) | 0.02 | |
| DBP (mmHg) | T0 | 80.78 (77.31;84.25) | ||
| T6 | 76.97 (73.07;80.87) | -3.81 (-8.79;1.16) | 0.13 | |
| T12 | 78.16 (74.63;81.68) | -2.62 (-7.34;2.1) | 0.27 | |
| Total cholesterol (mg/dl) | T0 | 174.14 (163.23;185.05) | ||
| T6 | 165.81 (151.1;180.52) | -8.33 (-23.08;6.41) | 0.26 | |
| T12 | 156.36 (143.88;168.85) | -17.78 (-29.67;-5.89) | 0.004 | |
| HDL cholesterol (mg/dl) | T0 | 45.51 (42.91;48.11) | ||
| T6 | 43.91 (41.16;46.65) | -1.6 (-4.06;0.85) | 0.20 | |
| T12 | 43.91 (40.17;47.65) | -1.6 (-5.62;2.41) | 0.43 | |
| LDL cholesterol (mg/dl) | T0 | 106.02 (96.81;115.24) | ||
| T6 | 100.65 (89.77;111.54) | -5.37 (-17.83;7.08) | 0.39 | |
| T12 | 96.04 (85.93;106.14) | -9.99 (-21.4;1.42) | 0.09 | |
| Triglycerides (mg/dl) | T0 | 174.79 (154.6;194.97) | ||
| T6 | 153.83 (131.93;175.73) | -20.96 (-44.71;2.8) | 0.08 | |
| T12 | 166.27 (144.36;188.18) | -8.52 (-27.54;10.51) | 0.38 | |
| SF36 - PCS | T0 | 43.82 (42.09;45.56) | ||
| T6 | 45.64 (43.46;47.83) | 1.82 (-0.63;4.27) | 0.14 | |
| T12 | 46.65 (44.49;48.82) | 2.83 (-0.02;5.68) | 0.05 | |
| SF36 - MCS | T0 | 33.24 (30.6;35.89) | ||
| T6 | 37.21 (34.67;39.75) | 3.97 (0.76;7.17) | 0.02 | |
| T12 | 36.5 (33.75;39.25) | 3.26 (0.07;6.45) | 0.045 | |
| DTSQ score | T0 | 27.28 (25.03;29.53) | ||
| T6 | 32.96 (30.84;35.07) | 5.68 (2.59;8.77) | 0.0005 | |
| T12 | 32.29 (30.73;33.85) | 5.01 (2.5;7.53) | 0.0002 |
*Paired t-test derived from linear mixed models for repeated measurements. Statistically significant p-values (<0.05) are in bold text.