Figure 11. AVE0991 treatment did not improve kidney function in female mice with SSHTN.
(A) 24-h urine excretion and (B) fractional excretion of sodium (FENa) in control, SSHTN, and SSHTN+AVE female mice. Results are presented as mean ± SEM and all statistical analyses were performed with one-way ANOVA s (n = 4–5 per group). *P<0.05 vs control mice and #P<0.05 vs SSHTN mice.