Figure 12. AVE0991 treatment differentially affected immune cells and inflammation in the ovaries of female mice with SSHTN.
Flow cytometric data examining ovarian populations of (A) M1 macrophages, (B) M2 macrophages, (C) DCs, (D) NK cells, and (E) T cells in control, SSHTN, and SSHTN+AVE female mice (n = 4–5 per group). Each cell population is shown as a percentage of its respective parent population. (F) Ovarian cytokine expression changes in control, SSHTN, and SSHTN+AVE female mice (n = 5–6 per group). Results are presented as mean ± SEM and statistical analyses were performed with one-way ANOVA. *P<0.05 vs control mice and #P<0.05 vs SSHTN mice.