TABLE 3.
Serological markers for early detection of intestinal stenosis.
| Markers | Potency | Correlation to fibrosis | Reference |
|---|---|---|---|
| pANCA | Prediction | Positive | Sarter H, et al 68 |
| MMP‐1, PAPP‐A, IGFBP‐2 | Diagnosis | Positive | Choung RS, et al 69 |
| KIT, FAP, NTRK2 | Negative | ||
| Bacterial flagellin antigens | Diagnosis | Positive | Bourgonje AR, et al 70 |
| Oscillospira | Diagnosis | Negative | Zhan S, et al 41 |
| PEO‐, SM, CE, LCDCA, ST | Diagnosis | Positive/Negative | Ferru‐Clément R, et al 71 |
Abbreviations: CE, cholesterol ester; FAP, fibroblast activation protein; IGFBP‐2, insulin‐like growth factor binding protein 2; LCDCA, long‐chain dicarboxylic acid; MMP‐1, matrix metalloproteinase‐1; NTRK2, neurotrophic tyrosine kinase receptor; pANCA, perinuclear anti‐neutrophil cytoplasmic antibody; PAPP‐A, pregnancy‐associated plasma protein A; PEO, phosphatidylethanolamine ether; SM, sphingomyelin; ST, sitosterol sulfate.