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. 2024 Jul 1;56(7):1397–1411. doi: 10.1038/s41588-024-01798-4

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© The Author(s) 2024, corrected publication 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a, Proportion of GWAS signals for AAM by early childhood weight trajectory. b, Biological pathways enriched for high-confidence AAM genes (left), plus enrichment within early childhood weight trajectories (right). Pathway enrichment was calculated using g:Profiler, and the displayed P values are Bonferroni-corrected. Row names describe pathway clusters. Strength of associations with individual pathways is indicated by circles. Circle size reflects the proportion of pathway genes that are high-confidence AAM genes (in percentage). Right, determining whether each pathway cluster remains enriched for AAM genes when stratified by early childhood weight trajectory. Supporting data are included in Supplementary Tables 21 and 23–26.