Table 1.
Important food allergens
| Food Allergen | Clinical Significance | |
|---|---|---|
| Cow's milk | Alpha-casein (Bos d 8) | Bos d 8 is associated with reactivity to extensively heated milk and persistent allergy |
| Alpha-lactalbumin (Bos d 4) | ||
| Beta-lactoglobulin (Bos d 5) | ||
| Bovine serum albumin (Bos d 6) | ||
| Hen's egg | Ovomucoid (Gal d 1) | Gal d 1 is associated with reactivity to extensively heated egg and persistent allergy |
| Ovalbumin (Gal d 2) | Gal d 5 is implicated with bird-egg syndrome | |
| Ovotransferrin (Gal d 3) | ||
| Alpha-livetin (Gal d 5) | ||
| Peanut | Ara h 1 | Ara h 1, 2, 3, 6 have a higher risk for systemic reactions |
| Ara h 2 | Ara h 2 may gain favor over whole peanut extract in diagnostic testing | |
| Ara h 3 | ||
| Ara h 6 | ||
| Ara h 8 | Ara h 8 is a Bet v 1 homologue | |
| Ara h 9 | ||
| Soy | Gly m 3 | |
| Gly m 4 | Gly m 4 is a Bet v 1 homologue but may still provoke severe reactions | |
| Gly m 5 | ||
| Gly m 6 | ||
| Hazelnut | Cor a 1 | Cor a 1 is a Bet v 1 homologue |
| Cor a 8 | Cor a 8, 9, 14 are associated with severe reactions | |
| Cor a 9 | ||
| Cor a 14 | ||
| Wheat | Omega-5-gliadin | Omega-5-gliadin is implicated in wheat-dependent, exercise-induced anaphylaxis and severe reactions |
| Tri a 36 | Tri a 36 associated with immunoglobulin E–mediated allergy | |
| Shrimp | Tropomyosin (Pen a 1) | May cross-react with proteins in dust mite and cockroach |