TABLE 2.
Binding of sera from SF2 and CM235 gp120-immunized baboons and of HIV-1 serum pools to rgp120 from clades B and E
| Samplea | Binding (RU)b
|
|
|---|---|---|
| rgp120SF2 | rgp120CM235 | |
| SF2-immunized baboons | ||
| US B pool | 692 | |
| B54 | 447 | |
| B55 | 1,539 | |
| B56 | 502 | |
| B57 | 812 | |
| B58 | 276 | |
| Meanc | 715 | |
| CM235-immunized baboons | ||
| Thai E pool | 1,802 | |
| B62 | 847 | |
| B63 | 552 | |
| B64 | 687 | |
| B65 | 1,300 | |
| B66 | 986 | |
| B67 | 841 | |
| B68 | 1,072 | |
| B69 | 1,041 | |
| B70 | 120 | |
| B71 | 683 | |
| Meand | 1,118 | |
a
B54 to B58 were immunized with rgp120SF2, and B62 to B71 were immunized with rgp120CM235, as described in Table 1. US B and Thai E pools are pools of individual sera (n = 25 each) from HIV-1-infected individuals known to be infected with clade B and clade E HIV-1, respectively.
b
Values for individual serum samples represent corrected binding after subtraction of background from preimmune sera as described in Materials and Methods.
c
Arithmetic mean of the five SF2-immunized baboons.
d
Arithmetic mean of the 10 CM235-immunized baboons.