Table 1.
Patient No. | Year | Sex | Race | Ethnicity | FPIES Food Trigger(s) | IgE-mediated FA | AD | Age at PN Introduction, mo | Onset of Symptoms, hr | Clinical Features | Therapy | PN SPT Result | OFC |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2018 | M | Caucasian | Non-Hispanic | PN | No | No | 5 | 3 | Vomiting, pallor, lethargy | Oral hydration | Negative* | No |
2 | 2019 | M | Caucasian | Non-Hispanic | PN, rice | Milk | No | 24 | 3 | Vomiting | Oral hydration | Negative (0-mm wheal, 3-mm flare) | No |
3 | 2019 | M | Caucasian | Non-Hispanic | PN, avocado | No | No | 7 | 4 | Vomiting, lethargy | Oral hydration | Negative (0-mm wheal, 0-mm flare) | Yes (failed at 15 mo) |
4 | 2019 | M | Asian | Non-Hispanic | PN | Egg | Yes | 6 | 1.5 | Vomiting, diarrhea, pallor | Oral hydration, IVF, oral ondansetron, IM epinephrine | Positive (4-mm wheal, 4-mm flare) | Yes (failed at 7 mo) |
5 | 2019 | F | Caucasian | Non-Hispanic | PN, avocado | Egg | Yes | 7 | 2 | Vomiting, pallor, lethargy | Oral hydration, oral ondansetron | Positive (6-mm wheal, 19-mm flare) | Yes (failed at 7 mo) |
FPIES = Food protein-induced enterocolitis syndrome; IgE = immunoglobulin E; FA = food allergy; AD = atopic dermatitis; PN = peanut; SPT = skin-prick test; OFC = oral food challenge; IVF = intravenous fluids; IM, intramuscular;
= refers to reported negative test (external testing).