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. 2023 Nov 28;40(7):963–980. doi: 10.1007/s12264-023-01149-z

Table 2.

Application of scRNA-seq in cochlear SGN.

Main idea Year Title Journal Species Method Data source
Cochlear SGN heterogeneity 2020 Single-Cell RNA Analysis of Type I Spiral Ganglion Neurons Reveals a Lmx1a Population in the Cochlea Frontiers in Molecular Neuroscience Mouse
2018 Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System Cell Mouse 10x Genomics GSE114759
2021 Diversity of developing peripheral glia revealed by single-cell RNA sequencing Developmental Cell Mouse inDrops GSE172110
Cochlear SGN development and aging 2022 Profiling mouse cochlear cell maturation using 10× Genomics single-cell transcriptomics Frontiers in Cellular Neuroscience Mouse 10x Genomics GSE202920
2022 Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages Cell Reports Mouse 10x Genomics GSE178931
2022 Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification Nature Communications Mouse Smart-seq2 GSE165502
2022 Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse PNAS Mouse 10x Genomics GSE195500
Cochlear SGN damage and disease 2021 A cell-type-specific atlas of the inner ear transcriptional response to acoustic trauma Cell Reports Mouse 10x Genomics GSE168041
2022 In silico Single-Cell Analysis of Steroid-Responsive Gene Targets in the Mammalian Cochlea Frontiers in Neurology Mouse
2022 Repurposable Drugs That Interact with Steroid Responsive Gene Targets for Inner Ear Disease Biomolecules Mouse

N.A., not available; SI, supporting information; –, no raw data was produced.