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. 2024 Jul 16;7:865. doi: 10.1038/s42003-024-06529-3

Fig. 1. Functional elements of AAV-TRES6 vector constructs.

Fig. 1

Depicted are schemes of the AAV-TRES6hu SGSG/GSGS, the AAV-TRES6hu LCV, and the AAV-TRES6 vector constructs. ITR inverted terminal repeat, VH variable region of the immunoglobulin heavy chain of the TRES6 antibody, CH-huIgG1 constant region of human IgG1 heavy chain, CH-muIgG2c constant region of the murine IgG2c heavy chain, SGSG/GSGS serine/glycine linker, F2A F2A self-cleaving peptide of the foot-and-mouth disease virus, VL variable region of the immunoglobulin light chain of TRES6 antibody, C-hu-Igk constant region of the human kappa light chain, C-mu-Igk constant region of the murine kappa light chain, WPRE woodchuck hepatitis virus posttranscriptional regulatory element, hGH polyA signal human growth hormone polyadenylation signal.