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. 2024 Jul 15;14:16302. doi: 10.1038/s41598-024-65439-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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DNA methylation in patient-derived GSFs. (A) percent methylation at each individual CpG site in the AR 5′UTR of the patient (excluding the L1 insertion) and two healthy controls. Genomic coordinates on the xaxis are given in the hg38 assembly and include only the wild type sequence in the patient and two healthy controls. (B) Percent methylation at individual CpG sites in patient-derived cells, including the L1 insertion (in green) and the adjacent regions. Position of the CpGs in the region of interest sequenced by nanopore is given on the xaxis.