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. 2024 May 29;43(14):3009–3026. doi: 10.1038/s44318-024-00128-y

Figure 7. The overall composition of C4BP changes during acute phase events.

Figure 7

The ratio of C4BPα to C4BPβ (blue bars) is shown on the primary y-axis (left). The concentrations of unbound ProS (teal) and C-reactive protein (red) are shown on the secondary y-axis (right). The data covers two healthy donors (C1 and C2) and two kidney transplant patients (P1 and P2). The gray area highlights the expected C4BPα/C4BPβ range of values (6 to 7) corresponding to solely α6β1(+ProS) and α7β1(+ProS) variants, as resolved by single-particle detection techniques. Source data are available online for this figure.