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. 2024 Jul 15;14:16303. doi: 10.1038/s41598-024-67072-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Box and whisker plots for the 1-year changes in the measurements of the clinical severity of ataxia 1-year changes in the SARA (A) and FARS II (B). SARA: Scale for the Assessment and Rating of Ataxia, and FARS: Friedreich Ataxia Rating Scale. The upper and lower margins of the rectangle represent the first and third quartiles, respectively. The horizontal line within the box represents the median value. The upper and lower vertical lines represent ranges or distances of 1.5 times the interquartile range from the first or third quartile values, respectively. ^*P < 0.05.