Table 3.
Literature review
| year | pmid | Case | gender | age | hypertension | hypopotassemia | pathologic changes in the adrenal glands | Tumor volume | specific immunohistochemistry | Mutation Gene | Obvious CS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022 | 35,960,046 | 1 | female | 53 | yes | yes | right adrenocortical adenoma | 3 cm × 2.3 cm × 1.7 cm | CYP11B1(+), CYP11B2(+), CaSR(+), VD3R(+), PTH1R (+) | - | no |
| 2022 | 35,960,046 | 2 | male | 59 | yes | no | right adrenocortical adenoma | 2.5 cm × 2.2 cm × 2 cm | CYP11B1(+), CYP11B2(+), CaSR(+), VD3R(+), PTH1R (+) | - | no |
| 2022 | 35,707,125 | 1 | female | 49 | yes | yes | right adrenocortical adenoma, light yellow | 2 cm × 1.7 cm × 1 cm | - | - | no |
| 2022 | 35,399,924 | 1 | female | 46 | yes | yes | bilateral adrenal glands multiple aldosterone-producing micronodules(mAPM), aldosterone adenoma | 1.6 cm(right), 2.1 cm(left) | CYP11B2(right, +), CYP11B1(left, +) | KCNJ5 (right side); PRKACA (left side) | no |
| 2021 | 34,657,370 | 1 | male | 34 | yes | yes | right adrenocortical adenoma | 6.3 cm × 6 cm | CYP11B2(+), CYP11B1(-) | - | no |
| 2021 | 34,384,396 | 1 | female | 67 | yes | no | right Adrenal gland tumor | 2.5 cm × 2.2 cm | CYP11B1(+), CYP11B2(-) | - | yes |
| 2020 | 33,434,176 | 1 | female | 56 | yes | yes | left adrenal gland tumor, golden-orange | 4.5 cm × 3.1 cm × 3.2 cm | - | - | no |
| 2016 | 8,533,534 | 1 | female | 50 | yes | yes | right adrenal gland tumor, 2/3 golden yellow, 1/3 sepia | 30 mm | - | - | yes |
| 2014 | 25,228,847 | 1 | female | 29 | yes | yes | left adrenocortical adenoma, golden yellow | 2.1 cm × 1.6 cm | HSD3β1(+), P450-17A1(+) | - | no |
| 2011 | 22,071,263 | 1 | female | 70 | yes | yes | left adrenocortical adenoma, yellow | 2 cm | - | no | |
| 2011 | 21,297,325 | 1 | male | 52 | yes | yes | bilateral adrenal tumor | 4.0 cm × 2.5 cm ×2.6 cm(left), 1 cm × 2.5 cm × 2 cm(right) | 3β-HSD(+), P450C17(+) | - | no |
| 2010 | 20,186,151 | 1 | female | 57 | yes | yes | left adrenocortical adenoma | 2.9 cm × 3.1 cm | CYP17(+) | - | yes |
| 2010 | 20,186,151 | 2 | female | 49 | yes | yes | right adrenocortical adenoma | 3.5 cm | CYP17(+) | - | yes |
| 2010 | 20,463,748 | 1 | female | 54 | yes | no | right adrenal tumor, bilateral microAPA | 2.5 cm(right), 2.1 mm(right), 1.6 mm(left), 1.9 mm(left) | 3β-HSD(+), P450C17(+) | - | yes |
| 2008 | 18,772,856 | 1 | male | 62 | yes | yes | right adrenocortical adenoma, golden yellow | 4.5 cm × 4.5 cm × 4.0 cm | - | - | no |
| 2008 | 18,543,063 | 1 | male | 50 | yes | yes | bilateral adrenocortical adenoma, golden yellow | 1 cm × 1 cm(left), 1.1 cm × 0.8 cm (+) | 3β-HSD(+), P450C17(+) | - | no |
| 2007 | 17,541,216 | 1 | female | 35 | yes | yes | left adrenocortical adenoma, golden-yellow | 3 cm | P450c17(+) | - | no |
| 2007 | 17,379,961 | 1 | female | 57 | yes | no | right adrenal tumors, golden yellow with a few brown areas | 2.1 cm, 1.9 cm | SCC(+), 3β-HSD II(+), CYP 21(+), CYP 11 B1(+), CYP 17(+) | - | no |
| 2005 | 16,613,821 | 1 | female | 39 | yes | no | left adrenocortical adenoma | 3.0 cm X 2.5 cm | - | - | no |
| 2002 | 12,487,169 | 1 | female | 43 | yes | yes | right adrenocortical adenoma, golden yellow | 4 cm | 3β-HSD(+), P450 (aldo)(+), P450(11beta) (+) | - | yes |
| 2023 | - | 1 | female | 29 | yes | yes | right adrenocortical adenoma, grayish yellow-brown | 2.9 cm × 2.4 cm | CYP11B1(+), CYP11B2(+), LHCGR(+) | PRKACA | yes |