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. 2024 May 8;81(8):1776–1784. doi: 10.1161/HYPERTENSIONAHA.124.22856

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© 2024 The Authors.

Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 3. — Renin-angiotensin system components in rats and mice. A, Angiotensinogen (Agt) in plasma of 6 wild-type (WT) and 6 Ren^−/− mice measured by Western blot. ****P<0.0001, Student’s t test. B to D, Angiotensin (Ang) I, Ang II, and Ang-(1-12) in the blood, kidneys, and brains of 6 wild-type and 6 Ren^−/− mice. E and F, Ang I, Ang II, and Ang-(1-12) in the blood and hearts of 3 Sprague-Dawley rats. LLOQ indicates lower limit of quantification; and Tf, transferrin.