Table I.
Results of cases registered in the case registry
| ABO (No.=225) | Cases | RhD (No.=183) | Cases | Red cell antibodies (No.=317) | Cases |
|---|---|---|---|---|---|
| Normal ABO group | 90 | D+ | 15 | Major alloantibodies a | 91 |
| ABO subgroup | D− | Minor alloantibodies a | 12 | ||
| CisAB | 62 | RHD complete deletion | 31 | Cold antibodies | 27 |
| A subgroup | 7 | RHD-CE-D hybrid | 10 | Autoantibodies | 32 |
| B subgroup | 40 | D variant | Alloantibodies to HFA | 78 | |
| ABO discrepancy | Partial D | 26 | Alloantibodies to LFA | 5 | |
| Red cell antibody | 13 | Weak D | 9 | Interference | 7 |
| Decreased Ig | 9 | DEL | 21 | Negative | 22 |
| Paraprotein | 4 | Unspecified | 62 | Etc. c | 43 |
| D--/D-- | 1 | ||||
| Etc. b | 8 | ||||
a
Major alloantibodies were defined as alloantibodies to antigens that must be expressed in reagent red cell sets licensed by United States Food and Drug Administration (D, C, E, c, e, M, N, S, s, P1, Lea, Leb, K, k, Fya, Fyb, Jka, and Jkb). Minor alloantibodies were defined as alloantibodies other than major alloantibodies.
b
Cases in which comprehensive serologic typing was not performed.
c
Cases that remained inconclusive even after antibody identification based on the tube method and column agglutination using more than 30 reagent cells.
Ig: immunoglobulin; HFA: high frequency antigen; LFA: low frequency antigen.