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. 2023 Sep 4;42(7):1046–1050. doi: 10.1038/s41587-023-01937-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — Force directed layout of 10K-nearest neighbors was run on cosine distance graph (represented by edge thickness and shade). Nodes (genes and peaks) were split in 18 spatially co-detected modules using the Spinglass algorithm (a) and by technology of origin (b). Genes and peaks whose expression were associated with dopamine (m/z 674.2805) were enriched in module 4 and shown in (c).