Skip to main content
. 2024 Jul 16;14:16390. doi: 10.1038/s41598-024-66412-3

Table 2.

Presenting ocular features in patients with ocular syphilis.

Ocular feature All (n = 214) Women (n = 53) Men (n = 161) p value
Anatomic classification of uveitis23, n (%) [n = 212 eyes: 51 eyes of women, 161 eyes of men]‡
 Anterior 13 (6.1) 4 (7.8) 9 (5.6) 0.087*
 Intermediate 18 (8.5) 4 (7.8) 14 (8.7)
 Posterior 163 (76.9) 34 (66.7) 129 (80.1)
 Panuveitis 18 (8.5) 9 (17.6) 9 (5.6)
Anterior segment findings, n (%)
 Anterior chamber cells 96 (44.9) 29 (54.7) 61 (41.2) 0.083*
 Keratic precipitates 42 (19.6) 12 (22.6) 30 (18.6) 0.703*
 Posterior synechiae 24 (11.2) 4 (7.5) 20 (12.4) 0.488*
 Cataract 16 (7.5) 6 (11.3) 10 (6.2) 0.551*
 Conjunctival hyperemia 8 (3.7) 3 (5.7) 5 (3.1) 0.806*
 Keratitis 4 (1.9) 1 (1.9) 3 (1.9)  > 0.999†
 Nodular scleritis 3 (1.4) 3 (5.7) 0 (0.0) 0.015†
Posterior segment findings, n (%) [n = 212 eyes: 51 eyes of women, 161 eyes of men]§
 Vitritis 94 (44.3) 15 (28.8) 79 (49.4) 0.019*
 Papillitis 68 (32.1) 15 (28.8) 53 (33.1) 0.684*
 Retinal vasculitis 58 (27.4) 11 (21.2) 47 (29.4) 0.547*
 Retinitis 54 (25.5) 13 (25.0) 41 (25.6) 0.796*
 Choroiditis/chorioretinitis 30 (14.2) 8 (15.4) 22 (13.8) 0.624*
 Cystoid macular oedema 11 (5.2) 3 (5.8) 8 (5.0) 0.678*
 Exudative retinal detachment 9 (4.2) 2 (3.8) 7 (4.4) 0.752*
 Epiretinal membrane 6 (2.8) 0 (0.0) 6 (3.8) 0.340†
 Rhegmatogenous retinal detachment 3 (1.4) 0 (0.0) 3 (1.9) 0.999†
 Choroidal neovascularization 2 (0.9) 2 (3.8) 0 (0.0) 0.059†
 Neuroretinitis 1 (0.5) 0 (0.0) 1 (0.6)  > 0.999†

n = 214 eyes, 53 eyes of women and 161 eyes of men, unless otherwise stated.

*Generalized estimating equation models.

Fisher’s exact test.

Two eyes with isolated scleritis were excluded from the classification.

§Evaluation of posterior segment was not possible in 2 eyes (0.9%) of 2 patients due to media opacities.