TABLE 2.

Anti-HBsAg and anti-MV responses in mice inoculated with MV and MVHBs

Virus	Route of inoculation	Animal	Anti-HBsAg antibody titer (mIU/ml)			Anti-MV antibody
						OD450 by ELISAa			Neutralization titer (mIU/ml)
			Preimmunization	14 dpi	28 dpi	Preimmunization	14 dpi	28 dpi	Preimmunization	14 dpi	28 dpi
MV	i.n.	1	0	0	0	0.11	1.56	2.10	<490	<490	1,130
		2	—b	—	—	0.10	1.06	1.06	—	<320	<370
		3	—	—	—	0.08	1.16	1.33	—	<400	570
		4	—	—	—	0.11	1.53	1.76	—	<380	1,630
	i.p.	5	0	0	0	0.11	1.90	2.04	<330	2,000	3,380
		6	—	—	—	0.14	1.65	2.00	—	1,740	8,370
		7	—	—	—	0.23	1.90	2.06	—	1,130	3,050
		8	—	—	—	0.22	1.75	2.04	—	480	2,990
MVHBs	i.n.	9	0	18.8	93.0	0.22	0.62	1.54	<380	<380	<380
		10	0	0	0	0.09	0.46	0.60	—	<380	<380
		11	0	0	0	0.13	0.33	0.29	—	<380	<380
		12	0	9.6	80.8	0.13	0.19	1.10	—	<380	<320
	i.p.	13	0	27.5	100.5	0.13	1.70	2.01	<380	900	2,300
		14	0	11.9	42.0	0.13	1.73	1.93	—	3,290	4,330
		15	0	0	41.4	0.17	1.50	1.61	—	450	770
		16	0	73.3	61.0	0.21	1.63	1.91	—	480	8,070

^aELISA reading at a 1:100 dilution of serum. 

^b—, not done.