Fig. 5.

Phylogenetic reconstruction∗ of closely related Lineage 4.1.1.1 M. tuberculosis genomes. UK genomes marked in blue and Australian genomes marked in orange. Nodes labelled with estimated time of divergence (95% highest probability density intervals). Columns show predicted drug resistance in red. RIF-Rifampicin, INH-Isoniazid, PZA-Pyrazinamide, ETB-Ethambutol and STR-Streptomycin. ∗Bayesian phylogenetic reconstruction using the best evolutionary model (relaxed lognormal clock, Hasegawa–Kishino–Yano substitution and exponential demographic).