TABLE 4.
gp70+ cells in each subpopulation
| Wk p.i. | Virus | % of gp70+ cells in subpopulationa
|
||||
|---|---|---|---|---|---|---|
| CD3− CD4− CD8− | CD3− CD4+ CD8+ | CD3+ CD4+ CD8+ | CD3+ CD4− CD8+ | CD3+ CD4+ CD8− | ||
| 3 | WT | 2.3 ± 0.8 | 5.9 ± 1.6 | 8.7 ± 1.9 | 13.6 ± 3.5 | 4.5 ± 1.1 |
| ΔNF-κB | 1.1 ± 0.9 | 0.8 ± 0.2 | 2.9 ± 0.3 | 5.5 ± 3.1 | 2.7 ± 0.9 | |
| ΔDEN | 0.8 ± 0.3 | 0.6 ± 0.2 | 2.7 ± 0.3 | 3.4 ± 1.3 | 2.4 ± 0.3 | |
| 4 | WT | 1.3 ± 0.6 | 28.3 ± 13.4 | 34.6 ± 16.4 | 18.5 ± 10.4 | 17.5 ± 10.1 |
| ΔNF-κB | 1.1 ± 0.3 | 5.6 ± 3.3 | 8.4 ± 5.3 | 6.5 ± 1.6 | 4.7 ± 1.7 | |
| ΔDENb | 1.2 ± 0.0 | 6.7 ± 0.0 | 10.1 ± 0.0 | 3.2 ± 0.0 | 3.2 ± 0.0 | |
| 6 | WT | 3.3 ± 1.9 | 43.3 ± 2.8 | 51.4 ± 1.8 | 23.9 ± 2.4 | 24.6 ± 3.6 |
| ΔNF-κB | 1.4 ± 0.8 | 23.1 ± 10.9 | 29.9 ± 13.3 | 10.8 ± 3.7 | 12.0 ± 5.5 | |
| ΔDENb | 1.3 ± 0.8 | 33.0 ± 16.7 | 43.2 ± 20.4 | 17.4 ± 7.4 | 13.3 ± 5.4 | |
| 8 | WT | 5.2 ± 2.5 | 50.8 ± 4.4 | 59.0 ± 5.7 | 23.0 ± 4.5 | 27.7 ± 5.4 |
| ΔNF-κB | 1.8 ± 0.8 | 34.5 ± 6.4 | 43.9 ± 5.1 | 13.7 ± 3.9 | 15.2 ± 3.0 | |
| ΔDENb | 1.7 ± 1.0 | 50.2 ± 9.6 | 44.9 ± 4.8 | 15.7 ± 2.7 | 16.5 ± 2.1 | |
a
Values are means ± standard deviations of the percentages of gp70+ cells in the T-cell subpopulations. Each subpopulation was selected by the Paint-a-Gate software, and the percentage of gp70+ cells of each subpopulation was calculated. Thymuses from one to seven mice, which were inoculated with medium or WT, ΔNF-κB, or ΔDEN MCF13 virus, were individually analyzed for each time point.
b
Thymuses from only ΔDEN-high mice were analyzed.