TABLE 5.
Phenotypes of thymic lymphomasa
| Virus | Lymphoma | % of tumor cells in thymic subpopulation
|
||||
|---|---|---|---|---|---|---|
| CD3− CD4− CD8− | CD3− CD4+ CD8+ | CD3+ CD4+ CD8+ | CD3+ CD4− CD8+ | CD3+ CD4+ CD8− | ||
| WT | 1 | 0.5 | 19.1 | 61.3 | 2.6 | 14.3 |
| 2 | 0.1 | 10.0 | 83.1 | 4.9 | 1.3 | |
| 3 | 0.1 | 11.0 | 85.1 | 2.1 | 0.8 | |
| 4 | 0.1 | 0.6 | 7.8 | 90.7 | 0.0 | |
| 5 | 0.2 | 3.1 | 92.4 | 3.0 | 0.5 | |
| 6 | 0.1 | 9.8 | 74.8 | 11.4 | 0.7 | |
| 7 | 0.3 | 0.6 | 97.3 | 0.3 | 1.1 | |
| 8 | 0.0 | 0.4 | 93.6 | 0.4 | 5.3 | |
| 9 | 0.8 | 0.6 | 68.7 | 9.4 | 13.7 | |
| 10 | 0.4 | 40.6 | 51.7 | 1.9 | 2.4 | |
| 11 | 0.4 | 16.4 | 70.2 | 1.3 | 9.0 | |
| ΔNF-κB | 1 | 0.1 | 2.5 | 33.3 | 59.6 | 0.3 |
| 2 | 0.4 | 3.7 | 90.8 | 3.7 | 0.4 | |
| 3 | 0.1 | 2.4 | 91.4 | 5.0 | 0.5 | |
| 4 | 0.5 | 2.8 | 79.4 | 1.4 | 13.8 | |
| ΔDEN | 1 | 0.4 | 5.5 | 78.1 | 0.9 | 13.4 |
| 2 | 1.5 | 30.9 | 60.7 | 0.5 | 3.8 | |
| 3 | 0.1 | 1.5 | 84.1 | 0.1 | 14.0 | |
| 4 | 7.6 | 4.6 | 35.7 | 40.7 | 2.2 | |
| 5 | 0.2 | 0.3 | 15.1 | 0.5 | 80.7 | |
a
T-cell phenotype of cells isolated from individual thymic lymphomas induced by WT, ΔNF-κB, or ΔDEN MCF13 virus.