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. 2024 Jun 13;39:100805. doi: 10.1016/j.bbih.2024.100805

Fig. 1.

Fig. 1

Representative paired neuroimaging and chest CT findings from COVID-19 patients presenting neurological symptoms. (A) Subject #16 (65 y/o; male) with encephalitis and a positive result for SARS-CoV-2 RT-qPCR in the CSF screening. Initial symptoms of fever and vomiting, evolving with drowsiness, ataxia, acute diplopia and convergent strabismus. No signs of viral pneumonia were detected on the CT scan. Case previously reported (Freitas et al., 2021). (B) Subject #25 (83 y/o; male; deceased) with acute CNS ischemic lesions (vasculitis); viral pneumonia, fever, respiratory distress, and rhabdomyolysis. Coronal chest CT images (lung window) show multiple areas of round ground-glass opacities, mainly on the right lung, with increasing extent after three days. (C) Subject #14 (50 y/o; female) presented acute demyelinating brain lesions and COVID-19 pneumonia. Axial CT images show areas of consolidation distributed predominantly at peripheral and posterior areas of the lower lobes and improvement in lung infiltrates after 17 days. (D) Subject #27 (29 y/o; female; deceased) with a previous diagnosis of Systemic Lupus Erythematosus, presenting CNS vasculitis; refractory epileptic status; and viral pneumonia. Evolution to progressive global systemic failure. Chest CT shows mild round ground-glass opacity on the middle lobe and upper right lung. Eleven days later, abnormalities increased with diffuse consolidation, mainly in the lower lobes. (E) Subject #23 (78 y/o; male; deceased) presented a subacute ischemic stroke with an altered level of consciousness, seizures, and coma; viral pneumonia. Axial CT images show no lung parenchymal findings consistent with viral pneumonia that progresses to mild patchy ground-glass opacity in the lungs' periphery 17 days after. Lung abnormalities are almost entirely resolved after 41 days. Subjects (B–E) with positive RT-qPCR for SARS-CoV-2 in the nasopharyngeal swab. Abbreviations: FLAIR, DWi, ADC, T1, T1 Gd+, T2 refer to MRI sequences, and Gd + represents venous contrast. Time of flight (TOF) arterial angiographic MRI sequence.