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. 2024 Jul 16;29:366. doi: 10.1186/s40001-024-01936-y

Table 5.

Patient characteristics and HRD score from clinical cohort

HRD score high (n = 28) HRD score low (n = 22) OR 95% CI P value
Age 0.58–5.62 0.310
 > 40 years 10 11 1
 ≤ 40 years 18 11 1.8
BMI(kg/m^2) 0.54–6.67 0.320
 < 25 18 17 1
 ≥ 25 10 5 1.89
BRCA status 1.69–44.34 0.011
 Non-mutated 15 20 1
 Mutated 13 2 8.67
Menopause 0.11–2.72 0.730
 Pre- 25 18 1
 Post- 3 4 0.54
ER 0.10–1.02 0.050
 Negative 18 8 1
 Positive 10 14 0.32
PR 0.10–1.05 0.057
 Negative 19 9 1
 Positive 9 13 0.33
Ki-67 1.33–25.05 0.032
 < 20% 3 9 1
 ≥ 20% 25 13 5.77
Molecular subtype 1.02–10.72 0.042
 Non-TNBC 11 15 1
 TNBC 17 7 3.31

HRD score high: HRD score ≥ 10; HRD score low: HRD score < 10 for AcornHRD

OR: odds ratio, CI: confidence interval, Pre-: premenopause, Post-: postmenopause