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. 2024 Jun 6;15(7):e01220-24. doi: 10.1128/mbio.01220-24

Fig 3.

Ribbon diagram of the structure of BT4124 RR with helices and strands labeled; expanded view of the interface between REC and DBD domains; and hydrogen bond network between side chains of conserved residues at the interdomain interface.

Predicted structure of an HTCS RR suggests interaction between the REC and DBD domains. (A) Ribbon view of the BT4124-RR structure predicted by AlphaFold 2. The highest ranked structure is shown. The REC domain is colored blue, and the DBD domain is colored red with the two DNA-recognizing helices highlighted in gold. (B) The interaction surface (green) of the REC domain that contacts the DBD. (C) Predicted contact residues at the REC-DBD interface.