Fig 5.

Prophylactic studies. Mice were dosed with mAb or bsAb as indicated and then challenged intranasally with 5× or 25× LD₅₀ of IAV A/Singapore/GP1908/2015 (IVR-180; pH1N1). Experiments were performed twice independently with two different groups (n = 5) and then the data were combined, except for the cocktail (1G01 + CR9114), which consisted of a single group of n = 5 mice performed once. An irrelevant Sudan virus-specific mAb (F4) was used as a control (***P < 0.001 and *P < 0.05, relative to F4).