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. 2024 Jul 3;11:1390232. doi: 10.3389/fnut.2024.1390232

Table 5.

Summary of the association between human milk composition and maternal age.

Paper Feeding type HM measured time-point HM component Maternal age measure time-point Reported associations and correlations Confounders adjusted
Chan et al. (12) EBF for 3–4 months 3 months Adiponectin (ng mL−1) 3 months No significant correlation observed Maternal BMI, pre-pregnancy weight, gestational weight gain, mode of infant feeding (exclusively or partially breastfed without formula at 3 months postpartum)
Leptin (ng mL−1) Concentrations were lower in older women (p = 0.05)
Insulin (ng mL−1) No significant correlation observed
Pundir et al. (28) EBF for 3+ months 3 months Cortisol (ng/mL) 3 months No significant effect observed Maternal BMI, education, occupational class, family income, family structure, seasonal variation, maternal distress, pregnancy duration, delivery and gestational diabetes
Zielinkska-Pukos et al. (41) EBF for 3+ months 1, 3 and 6 months Cortisol (ng/mL) 1, 3 and 6 months No significant correlation observed None

Where confounders were adjusted, data reported is from adjusted analysis. Significant results are depicted with the p value in bold. HM, human milk; EBF, exclusive breastfeeding; BMI, body mass index.