Table 7. Distribution of HPV types according to tumour type in women with histologically confirmed ICC infected with a single HPV type.
| HPV serotypes | SCC (n = 51(%)) | ASC/ADC (n = 7(%)) |
Others (n = 8(%)) |
Test statistics | p-value |
|---|---|---|---|---|---|
| HPV 6 | |||||
| Positive | 1 (2.0) | 0 (0) | 0 (0) | χ2 = 0.299 | 0.861 |
| Negative | 50 (98.0) | 7 (100.0) | 8 (100.0) | ||
| HPV16 | |||||
| Positive | 38 (74.5) | 3 (42.9) | 3 (37.5) | χ2 = 7.362 | 0.025 |
| Negative | 13 (25.5) | 4 (57.1) | 5 (62.5) | ||
| HPV18 | |||||
| Positive | 6 (11.8) | 0 (0) | 1 (12.5) | χ2 = 0.933 | 0.627 |
| Negative | 45 (88.2) | 7 (100) | 7 (87.5) | ||
| HPV31 | |||||
| Positive | 12 (23.5) | 3 (42.9) | 2 (25.0) | χ2 = 1.205 | 0.547 |
| Negative | 39 (76.5) | 4 (57.1) | 6 (75.0) | ||
| HPV33 | |||||
| Positive | 12 (23.5) | 3 (42.9) | 2 (25.0) | χ2 = 1.205 | 0.547 |
| Negative | 39 (23.5) | 4 (52.9) | 6 (75.0) | ||
| HPV35 | |||||
| Positive | 2 (3.9) | 0 (0) | 0 (0) | χ2 = 0.607 | 0.738 |
| Negative | 49 (96.1) | 7 (100.0) | 8 (100.0) | ||
| HPV44 | |||||
| Positive | 1 (2.0) | 0 (0) | 0 (0) | χ2 = 0.299 | 0.861 |
| Negative | 50 (98.0) | 7 (100.0) | 8 (100.0) | ||
| HPV45 | |||||
| Positive | 4 (7.8) | 1 (14.3) | 1 (12.5) | χ2 = 0.437 | 0.804 |
| Negative | 47 (92.2) | 6 (85.7) | 7 (87.5) | ||
| HPV51 | |||||
| Positive | 2 (3.9) | 0 (0) | 0 (0) | χ2 = 0.607 | 0.738 |
| Negative | 49 (96.1) | 7 (100.0) | 8(100.0) | ||
| HPV56 | |||||
| Positive | 2 (3.8) | 0 (0) | (0) | χ2 = 0.607 | 0.738 |
| Negative | 49 (96.1) | 7 (100.0) | 8 (100.0) | ||
| HPV81 | |||||
| Positive | 23 (45.1) | 3 (42.9) | 1 (12.5) | χ2 = 3.052 | 0.217 |
| Negative | 28 (54.9) | 4 (57.1) | 7 (87.5) | ||
| HPV82 | |||||
| Positive | 0 (0) | 0 (0) | 1 (12.5) | χ2 = 7.996 | 0.015 |
| Negative | 51 (100.0) | 7 (100.0) | 7 (87.5) | ||
| HPV89 | |||||
| Positive | 1 (2.0) | 0 (0) | 0 (0) | χ2 = 0.299 | 0.861 |
| Negative | 50 (98.0) | 7 (100.0) | 8 (100.0) |
p < 0.05 are statistically significant, χ2 = Chi-square test
Key: squamous cell carcinoma (SCC (LSK SCC & LSNK SCC)). Adenosquamous carcinoma (ASC), Others (transitional cell carcinoma, undifferentiated squamous cell carcinoma and poorly differentiated squamous cell carcinoma.)