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Effect of supplement on the collagen density, structure, and fragmentation. Representative images from 1 subject in the treatment group and the placebo group are shown. Confocal images show low collagen density, poor structural integrity of fibres and a visible fragmentation at baseline for both groups. At week 12 there is an increase in collagen density, increased presence of fibrillar structures and a decrease in the fragmentation pattern for subjects using the AC supplement daily.
